Assistant Professor of Chemistry
on faculty since 2013
Ph.D., University of Chicago, Chicago, Illinois, 2014
M.S., University of Chicago, Chicago, Illinois, 2010
B.A., Calvin College, Grand Rapids, Michigan, 2009
Professional and Personal Interests
For Assistant Professor of Chemistry Mike Bosscher, being a good steward of God’s creation means studying and understanding its most intricate parts and helping his students to do the same.
“Proteins are made up of only 20 amino acids, yet they are able to accomplish many different tasks,” said Bosscher. “Learning about the amazing diversity of protein function gives us insight into the wisdom of the Creator just as my research on natural uranium binding motifs helps me understand how I can look after the gift of creation.”
Bosscher is thankful to be part of a community passionate about kingdom work, and he is excited about the opportunities to involve students in one form of kingdom work in particular: proteins that bind and detect heavy metals. “Students do not realize that at many colleges there are no opportunities for meaningful interactions with professors and others in the community. Trinity is intentional about cultivating these types of relationships–an intentionality that I have already seen pay huge dividends.”
His regard for the creation and the diversity of its intricate parts also translates to Bosscher’s valuing diversity among his students. Through a variety of experiences, Bosscher has learned about hospitality from diverse populations. “I am learning to empathize and interact with people by observing and asking questions,” said Bosscher. “Hospitality that finds the right questions to ask and goes out of its comfort zone can be vastly rewarding.”
You can read more about Mike Bosscher’s research interests here.
- General Chemistry
- Principles of Organic and Biochemistry
- Quantitative Analysis
- Environmental Chemistry
- Instrumental Methods of Analysis
- Biochemistry I
- Biochemistry II
- Advanced Inorganic Chemistry
Professional Society Membership
- American Chemical Society
Papers Published and/or Presented
Zhou, L.; Bosscher, M.; Zhang, C.; Ozcubukcu, S.; Zhang, L.; Zhang, W.; Li, C. J.; Liu, J.; Jensen, M. P.; Lai, L.; He, C. “A protein engineered to bind uranyl selectively and with femtomolar affinity” Nat. Chem. (2014), 6, 236-241.
Song, W. H.; Liu, M. M.; Zhong, D. W.; Zhu, Y. L.; Bosscher, M.; Zhou, L.; Ye, D. Y.; Yuan, Z. H.; “Tetrazole and triazole as bioisosteres of carboxylic acid: discovery of diketo tetrazoles as anti-HCV agents” Bioorg. Med. Chem. Lett. (2013), 23(16), 4528-4531.
Liang, H.; Deng, X.; Bosscher, M.; Ji, Q.; Jensen, M. P.; He, C. “Engineering Bacterial Two-Component System PmrA/PmrB to Sense Lanthanide Ions” J. Am. Chem. Soc. (2013), 135(6), 2037–2039.
Tasker, Sarah Z.; Bosscher, Michael A.; Shandro, Christina A.; Lanni, Erica L.; Ryu, Keun Ah; Snapper, Gregory S.; Utter, Jarrad M.; Ellsworth, Bruce A.; Anderson, Carolyn E. “Preparation of N-Alkyl 2-Pyridones via a Lithium Iodide Promoted O- to N-Alkyl Migration: Scope and Mechanism” J. Org. Chem. (2012), 77(18), 8220-8230.
He, C.; Zhou, L.; Bosscher, M. 2013, “Protein Scaffolds for Selective Enrichment of Metal Ions”. U.S. Patent 20110093964 A1, International Patent WO 2013154731 A1Lanni, Erica L.; Bosscher, Michael A.; Ooms, Bartel D.; Shandro, Christina A.; Ellsworth, Bruce A.; Anderson, Carolyn E. “Synthesis of Substituted N-Benzyl Pyridones via an O- to N-Alkyl Migration” J. Org. Chem. (2008), 73(16), 6425-6428.